yitT [2019-06-27 13:44:02]

general stress protein, required for protection against paraquat stress

locus: BSU11120

pI: 9.50

mw: 30.38 kDa

protein length: 280 aa

gene length: 843 bp

function: protection against paraquat stress

product: unknown

essential: no

synonyms: yuxA

Genomic Context

categories

• [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.1|General stress proteins (controlled by SigB)]
• [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.8|Resistance against oxidative and electrophile stress]
• [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]

Gene

Coordinates: 1,188,689 1,189,531

The protein

Protein family

• [SW|UPF0750 membrane proteins]

[SW|Localization]

• cell membrane (according to UniProt)

Expression and Regulation

Operons

• genes: [gene|07ABC6A548F1186B67B58C0E14915AC3FE94882E|yitT]-[gene|D5536B27AFF8ADE7FAEA9B815F2607FC33B66404|ipi]
  description: [Pubmed|27965289]

  sigma factors

  • [protein|580011DE5DC40EC9E7E0512791D328FAA010DCB8|SigB]: sigma factor, [Pubmed|15805528], in [regulon|580011DE5DC40EC9E7E0512791D328FAA010DCB8|SigB regulon]

  regulation

  • induced by stress ([protein|search|SigB]) [Pubmed|15805528]

Biological materials

Mutant

• MGNA-B209 (yitT::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1208 NBRP B. subtilis, Japan]
• BKE11120 ([gene|07ABC6A548F1186B67B58C0E14915AC3FE94882E|yitT]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE11120 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGGCATGTTCCTCCGCTC, downstream forward: _UP4_TGACGAAAGCAGGTGGAAGT
• BKK11120 ([gene|07ABC6A548F1186B67B58C0E14915AC3FE94882E|yitT]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK11120 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGGCATGTTCCTCCGCTC, downstream forward: _UP4_TGACGAAAGCAGGTGGAAGT

References

• 15805528,22582280,27965289